Overview
A position is immediately available for a Neuropathology Clinical Research Coordinator to join the Precision Medicine Program within the DFCI Department of Pathology. The applicant would be a member of Dr. Keith Ligon’s Lab and the Center for Neuro-oncology at Dana Farber Cancer Center. The candidate will be required to work with patients and providers to facilitate translational biomarker, data science, and spatial biology driven research by applying tissue and data management skills within the DFCI and Harvard Cancer Center. The position involves research in clinical trials, including trials of novel immunotherapies and targeted therapies related to brain tumors. The position will provide applicants with outstanding opportunities for interaction with patients, physicians, clinical research staff, and basic researchers in a dynamic and exciting environment.
The main goals of this position are to facilitate human research studies which depend on tissue and blood specimens from cancer patients, work with patients to support their consent and donations these translational research studies and help ensure that all pathology review and biomarker studies required as part of clinical trials is completed.
Activities of the position are performed by a group of neuropathology CRCs at the Department of Pathology. Activities include consenting patients and managing the regulatory components of precision medicine studies and pathology supported clinical trials at the local and national level. They will coordinate pathology review, spatial biology methods (spatial proteomics/transcriptomics), single cell sequencing, and biomarker research done in the Brain Tumor Program at Dana Farber Cancer Institute. Key projects for which the applicant would provide clinical research coordination support would include triage of next-generation sequencing of patient cohorts, clinical data abstraction to support tissue and cancer “avatars” studies of patient-derived cell lines and xenografts. The position will support single cell sequencing and cell free DNA studies of brain tumor patients and emerging technologies for multiplex imaging of tissue samples. Applicants will utilize REDCap, OncCore, Excel and hospital information systems and statistical software analysis tools to perform clinical research and outcomes data analysis for research publications. While not required, there are opportunities to utilize or work with other data tools (e.g. R programming).
We are considering spring 2025 Bachelor degree graduates for this position.
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow’s physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
Responsibilities
- Oversight of the clinical trials start-up process from receipt of protocols through the Scientific Review Committee and IRB submissions, and site activation activities.
- Responsible for data reporting, management, collection of source documents, use and development of case report forms, adverse events reporting, filing and archiving of study records, and resolution of data queries.
- Participate in analysis and interpretation of clinical research data with lab members.
- Prepare and or complete regulatory related reports and IRB submissions. Maintain and organize study regulatory data, enter all required study data on an ongoing basis.
- Ensure all study related samples are collected, properly prepared and shipped according to the protocol requirements and IATA/DOT regulations.
- Responsible for organizing and preparing for both internal and external auditing and study monitoring visits.
- Coordination and management of clinical trials, including communication with Sponsors and regulatory authorities.
- Close-out of clinical trials, including contributing to research articles, audit preparation, and communication with regulatory agencies and other disciplines involved.
- Interact with study participants as directed/required by the protocol and/or study team.
- Tissue sample handling, distribution, and occasional processing.
Qualifications
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Bachelor’s Degree or 1 year of Dana-Farber Associate Clinical Research Coordinator experience required.
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0-1 years of experience working in a medical or scientific research setting or comparable technology orientated business environment preferred.
KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED:
- Excellent organization and communications skills required.
- Strong interpersonal skills – ability to effectively interact with all levels of staff and externals contacts.
- Must be detail oriented and have the ability to follow-through.
- Ability to effectively manage time and prioritize workload.
- Must practice discretion and adhere to hospital confidentiality guidelines at all times.
- Must have computer skills including the use of Microsoft Office.
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
