Dan Winer and Julie Andersen Co-supervisor
The Winer and Andersen labs at the Buck Institute for Research on Aging are interested in studying how the immune system influences chronic inflammation during aging and neurodegenerative diseases of aging. We’re looking for an independent and highly motivated recent PhD or MD/PhD graduate with a strong background in immunology to study mechanisms of inflammation with age using mouse models and human samples. One focus of this project will be understanding the Gut-Brain axis in aging.
POSITION SUMMARY
The Winer lab at the Buck Institute studies how the immune system influences metabolic syndrome and aging (see sample lab papers: Tsai et al Cell Metab 2018, 922-34; Ghazarian et al Science Immunol 2017, Apr 21; Winer et al Cell Metab 2016, 413-26; Luck et al Cell Metab 2015, 527-42; Winer et al Nature Med 2011, 610-7; Winer et al Nature Med 2009; 921-9). We use immunology, molecular biology, including multi-omic assays, endocrinology, mouse models, and tissue culture assays to elucidate mechanisms by which immune cells and immune molecules influence inflammation in tissues.
The Andersen lab has a longstanding interest in understanding age-related mechanisms driving neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease (see sample lab papers: Chita et al Cell Rep. 2018, 930-940; Lee et al Mech Ageing Dev. 2021, 111585; Danielson SR. J Biol Chem 2011, 7601-8). The lab has an emerging interest in the role of the Gut-Brain axis in these conditions. Dr. Andersen is a full Professor at the Buck Institute for Research on Aging.
The selected applicant will have the unique opportunity to work under the guidance of two experts, one in immunology, and one in neurodegenerative diseases, on a joint project during this post-doctoral position. The position will involve using multiple approaches primarily in mouse models to better understand inflammation and the Gut-Brain axis during aging and neurodegenerative diseases.
